PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16375848-1	2006	Acute effects of free fatty acids (FFA) were investigated on: (1) glucose oxidation, and UCP-2 and -3 mRNA and protein levels in 1 h incubated rat soleus and extensor digitorium longus (EDL) muscles, (2) mitochondrial membrane potential in cultured skeletal muscle cells, (3) respiratory activity and transmembrane electrical potential in mitochondria isolated from rat skeletal muscle, and (4) oxygen consumption by anesthetized rats.	Fatty Acids, Nonesterified	17-33	uncoupling protein 2	Rattus norvegicus	89-101	
20010438-0	2010	The role of uncoupling protein 2 in the apoptosis induced by free fatty acid in rat cardiomyocytes.	Fatty Acids, Nonesterified	61-76	uncoupling protein 2	Rattus norvegicus	12-32	
20010438-2	2010	Evidence suggests that free fatty acids induce cellular apoptosis, and recent studies have shown that free fatty acids dramatically elevate mRNA levels of uncoupling protein 2 (UCP2) in some cell lines.	Fatty Acids, Nonesterified	23-39	uncoupling protein 2	Rattus norvegicus	155-175	
20010438-2	2010	Evidence suggests that free fatty acids induce cellular apoptosis, and recent studies have shown that free fatty acids dramatically elevate mRNA levels of uncoupling protein 2 (UCP2) in some cell lines.	Fatty Acids, Nonesterified	23-39	uncoupling protein 2	Rattus norvegicus	177-181	
20010438-2	2010	Evidence suggests that free fatty acids induce cellular apoptosis, and recent studies have shown that free fatty acids dramatically elevate mRNA levels of uncoupling protein 2 (UCP2) in some cell lines.	Fatty Acids, Nonesterified	102-118	uncoupling protein 2	Rattus norvegicus	155-175	
20010438-2	2010	Evidence suggests that free fatty acids induce cellular apoptosis, and recent studies have shown that free fatty acids dramatically elevate mRNA levels of uncoupling protein 2 (UCP2) in some cell lines.	Fatty Acids, Nonesterified	102-118	uncoupling protein 2	Rattus norvegicus	177-181	
20010438-3	2010	In this study, we investigated the possibility that free fatty acids induce the expression of UCP2 through the peroxisome proliferator-activated receptor pathway, thereby increasing cell apoptosis in adult rat cardiomyocytes.	Fatty Acids, Nonesterified	52-68	uncoupling protein 2	Rattus norvegicus	94-98	
20010438-5	2010	Quantitative real-time reverse transcription-polymerase chain reaction and Western blotting showed significant increases in the level of UCP2 expression at 6, 12, and at 24 hours after treatment of adult rat cardiomyocytes with free fatty acids.	Fatty Acids, Nonesterified	228-244	uncoupling protein 2	Rattus norvegicus	137-141	
20010438-6	2010	Expression of UCP2 was suppressed with RNA interference, and knockdown of UCP2 attenuated free fatty acid-induced apoptosis in the cardiomyocytes.	Fatty Acids, Nonesterified	90-105	uncoupling protein 2	Rattus norvegicus	74-78	
20010438-7	2010	In summary, free fatty acids induced UCP2 expression through peroxisome proliferator-activated receptor alpha in adult rat cardiomyocytes.	Fatty Acids, Nonesterified	12-28	uncoupling protein 2	Rattus norvegicus	37-41	
15602629-14	2005	Skeletal muscle UCP2 and -3 mRNA expression strongly correlated with the plasma free fatty acid concentration, whereas BAT UCP1 and hepatic UCP2 gene expression did not.	Fatty Acids, Nonesterified	80-95	uncoupling protein 2	Rattus norvegicus	16-20	
9177227-2	1997	Here we show that leptin alters in pancreatic islets the mRNA of the genes encoding enzymes of free fatty acid metabolism and uncoupling protein-2 (UCP-2).	Fatty Acids, Nonesterified	95-110	uncoupling protein 2	Rattus norvegicus	148-153	
12205102-2	2002	It is also known that chronic exposure of pancreatic islets to free fatty acids (FFAs) blunts glucose-stimulated insulin secretion and is accompanied by elevated levels of UCP2.	Fatty Acids, Nonesterified	63-79	uncoupling protein 2	Rattus norvegicus	172-176	
12397391-5	2002	Furthermore, such muscle-type dependency in fasting-induced transcriptional changes in UCP2, UCP3, carnitine palmitoyltransferase and medium-chain acyl-CoA dehydrogenase persists when the increase in circulating levels of free fatty acids during fasting is abolished by the anti-lipolytic agent nicotinic acid - with blunted responses only in the slow-twitch muscle contrasting with unabated increases in fast-twitch muscles.	Fatty Acids, Nonesterified	222-238	uncoupling protein 2	Rattus norvegicus	87-91	
10519137-0	1999	Skeletal muscle UCP3 and UCP2 gene expression in response to inhibition of free fatty acid flux through mitochondrial beta-oxidation.	Fatty Acids, Nonesterified	75-90	uncoupling protein 2	Rattus norvegicus	25-29	
10519137-6	1999	The mRNA levels of both UCP3 and UCP2 in response to etomoxir were significantly reduced in the tibialis anterior muscle in both fed and fasted states (P < 0.01), unaltered in the gastrocnemius muscle in both fed and fasted states and unaltered in the soleus muscle in the fed state, but increased in the fasted state, in parallel with the etomoxir-induced changes in serum FFA levels.	Fatty Acids, Nonesterified	377-380	uncoupling protein 2	Rattus norvegicus	33-37