PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32923762-0	2020	Humanin Ameliorates Free Fatty Acid-Induced Endothelial Inflammation by Suppressing the NLRP3 Inflammasome.	Fatty Acids, Nonesterified	20-35	NLR family pyrin domain containing 3	Homo sapiens	88-93	
9765239-13	1998	In the case of triacylglycerol hydrolysis, the respective Vmax values for (A-I/TG)rHDL and (A-II/TG)rHDL were 1154.8 and 240.2 nmol of NEFA formed/ml of HL/h.	Fatty Acids, Nonesterified	135-139	NLR family pyrin domain containing 3	Homo sapiens	92-96	
25825956-3	2015	Recent evidence suggests that activation of the innate immune system in the course of obesity is mediated by metabolic signals, such as free fatty acids (FFAs), being elevated in many obese subjects, through activation of pattern recognition receptors thereby leading to stimulation of critical inflammatory signaling cascades, like IkappaBalpha kinase/nuclear factor-kappaB (IKK/NF- kappaB), endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) and NOD-like receptor P3 (NLRP3) inflammasome pathway, that interfere with insulin signaling.	Fatty Acids, Nonesterified	136-152	NLR family pyrin domain containing 3	Homo sapiens	471-491	
28738323-1	2017	BACKGROUND: This study aimed to investigate whether exogenous hydrogen sulfide (H2S) can protect the RAW264.7 macrophages against the inflammation induced by free fatty acids (FFA) by blunting NLRP3 inflammasome activation via a specific TLR4/NF-kappaB pathway.	Fatty Acids, Nonesterified	176-179	NLR family pyrin domain containing 3	Homo sapiens	193-198	
30945564-0	2019	Vildagliptin inhibits high free fatty acid (FFA)-induced NLRP3 inflammasome activation in endothelial cells.	Fatty Acids, Nonesterified	27-42	NLR family pyrin domain containing 3	Homo sapiens	57-62	
30945564-0	2019	Vildagliptin inhibits high free fatty acid (FFA)-induced NLRP3 inflammasome activation in endothelial cells.	Fatty Acids, Nonesterified	44-47	NLR family pyrin domain containing 3	Homo sapiens	57-62	
30945564-8	2019	Mechanistically, we show that vildagliptin suppresses FFA-induced expression of proteins of the NLRP3 inflammasome complex, including NLRP3, ASC, p20 and HMGB-1, and mitigates FFA-induced inactivation of the AMPK pathway.	Fatty Acids, Nonesterified	54-57	NLR family pyrin domain containing 3	Homo sapiens	96-101	
30945564-8	2019	Mechanistically, we show that vildagliptin suppresses FFA-induced expression of proteins of the NLRP3 inflammasome complex, including NLRP3, ASC, p20 and HMGB-1, and mitigates FFA-induced inactivation of the AMPK pathway.	Fatty Acids, Nonesterified	54-57	NLR family pyrin domain containing 3	Homo sapiens	134-139	
31514535-0	2019	Cilostazol ameliorates high free fatty acid (FFA)-induced activation of NLRP3 inflammasome in human vascular endothelial cells.	Fatty Acids, Nonesterified	28-43	NLR family pyrin domain containing 3	Homo sapiens	72-77	
31514535-0	2019	Cilostazol ameliorates high free fatty acid (FFA)-induced activation of NLRP3 inflammasome in human vascular endothelial cells.	Fatty Acids, Nonesterified	45-48	NLR family pyrin domain containing 3	Homo sapiens	72-77	
25825956-3	2015	Recent evidence suggests that activation of the innate immune system in the course of obesity is mediated by metabolic signals, such as free fatty acids (FFAs), being elevated in many obese subjects, through activation of pattern recognition receptors thereby leading to stimulation of critical inflammatory signaling cascades, like IkappaBalpha kinase/nuclear factor-kappaB (IKK/NF- kappaB), endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) and NOD-like receptor P3 (NLRP3) inflammasome pathway, that interfere with insulin signaling.	Fatty Acids, Nonesterified	136-152	NLR family pyrin domain containing 3	Homo sapiens	493-498	
25202950-0	2014	[Effect of free fatty acid on NALP3 inflammasome signaling pathway in THP-1 macrophages].	Fatty Acids, Nonesterified	11-26	NLR family pyrin domain containing 3	Homo sapiens	30-35	
25202950-8	2014	CONCLUSION: ROS induced by free fatty acid can regulate the activation of NALP3 inflammasome signaling pathway leading to the release of inflammatory cytokines.	Fatty Acids, Nonesterified	27-42	NLR family pyrin domain containing 3	Homo sapiens	74-79	
25175736-0	2014	Free fatty acids as modulators of the NLRP3 inflammasome in obesity/type 2 diabetes.	Fatty Acids, Nonesterified	0-16	NLR family pyrin domain containing 3	Homo sapiens	38-43