PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24019516-2 2013 A CerS2 null mouse displays hepatopathy because of depletion of C22-C24 ceramides, elevation of C16-ceramide, and/or elevation of sphinganine. N-palmitoylsphingosine 96-108 ceramide synthase 2 Mus musculus 2-7 23283968-4 2013 Significant changes were observed in the sphingolipid profile of CerS2 null mouse liver, including elevated C16-ceramide and sphinganine levels in liver and in isolated mitochondrial fractions. N-palmitoylsphingosine 108-120 ceramide synthase 2 Mus musculus 65-70 23690971-4 2013 Furthermore, the ceramide species synthesis in the lung is homeostatically regulated, since mice lacking very long acyl chain C24-ceramides due to genetic deficiency of CerS2 displayed a ten-fold increase in C16-ceramides and C16-dihydroceramides along with elevation of acid sphingomyelinase and CerS5 activities. N-palmitoylsphingosine 208-221 ceramide synthase 2 Mus musculus 169-174