PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9718266-6	1998	These results suggest that the increased prostaglandin production by cyclooxygenase-2 could be responsible for enhancement of the acetic acid-induced writhing reaction by lipopolysaccharide pretreatment.	Acetic Acid	130-141	prostaglandin-endoperoxide synthase 2	Mus musculus	69-85	
33152433-6	2021	(2) Both the ESM and its active ingredients could effectively alleviate the degree of swelling of the auricle and toes, increase the threshold of heat pain, decrease the overexpression of inflammatory protein cyclooxygenase-2 (COX-2) in the skin tissue of the tested parts of the toes, and reduce the number of writhes induced by acetic acid in mice.	Acetic Acid	330-341	prostaglandin-endoperoxide synthase 2	Mus musculus	227-232	
21356364-9	2011	Induction of cyclooxygenase-2 in the stomach, in response to indomethacin- or acetic acid-induced ulceration, was significantly reduced in male Muc-2-deficient mice.	Acetic Acid	78-89	prostaglandin-endoperoxide synthase 2	Mus musculus	13-29	
24406787-6	2014	The ethyl acetate extract was also found to reduce the inflammation pain of acetic acid-induced writhing model in a dose-dependent manner and cause reduction of the ALI in mice through the inhibition of the release of PGE2 and the LPS-induced COX-2 expression in the lung.	Acetic Acid	76-87	prostaglandin-endoperoxide synthase 2	Mus musculus	243-248