PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12714508-5 2003 The hydroxamate GW280264X, capable of blocking TACE as well as ADAM10, proved to be an effective inhibitor of the constitutive and the PMA-inducible CX3CL1 cleavage in CX3CL1-expressing ECV-304 cells (CX3CL1-ECV-304), whereas GI254023X, preferentially blocking ADAM10 but not TACE, reduced the constitutive cleavage only. GW280264X 16-25 C-X3-C motif chemokine ligand 1 Homo sapiens 149-155 12714508-5 2003 The hydroxamate GW280264X, capable of blocking TACE as well as ADAM10, proved to be an effective inhibitor of the constitutive and the PMA-inducible CX3CL1 cleavage in CX3CL1-expressing ECV-304 cells (CX3CL1-ECV-304), whereas GI254023X, preferentially blocking ADAM10 but not TACE, reduced the constitutive cleavage only. GW280264X 16-25 C-X3-C motif chemokine ligand 1 Homo sapiens 168-174 12714508-5 2003 The hydroxamate GW280264X, capable of blocking TACE as well as ADAM10, proved to be an effective inhibitor of the constitutive and the PMA-inducible CX3CL1 cleavage in CX3CL1-expressing ECV-304 cells (CX3CL1-ECV-304), whereas GI254023X, preferentially blocking ADAM10 but not TACE, reduced the constitutive cleavage only. GW280264X 16-25 C-X3-C motif chemokine ligand 1 Homo sapiens 168-174