PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15885676-5	2005	The thrombin-induced activation of secreted MMP-2 was abolished by GTE and the green tea polyphenols (-)-epigallocatechin-3-gallate (EGCG) and (-)-epicatechin-3-gallate (ECG).	Polyphenols	89-100	coagulation factor II, thrombin	Homo sapiens	4-12	
35019268-8	2022	Our thrombin-responsive, polyphenol-based NPs represent a promising platform for advanced drug delivery applications, with potential to improve thrombolytic therapies.	Polyphenols	25-35	coagulation factor II, thrombin	Homo sapiens	4-12	
24610996-4	2014	The aim of our present study was to examine the effects of the well-known polyphenolic compounds on the activity of thrombin, by characterization of its interaction with selected polyphenols using different biochemical methods and biosensor BIAcore analyses.	Polyphenols	179-190	coagulation factor II, thrombin	Homo sapiens	116-124	
24610996-5	2014	Only six compounds, cyanidin, quercetin, silybin, cyanin, (+)-catechin and (-)-epicatechin, of all examined in this study polyphenols caused the inhibition of thrombin amidolytic activity.	Polyphenols	122-133	coagulation factor II, thrombin	Homo sapiens	159-167	
15342215-8	2004	Augmented respiratory burst of neutrophils in response to thrombin-activated platelets was also inhibited by the two polyphenols as was neutrophil migration toward thrombin-induced supernatants of platelets.	Polyphenols	117-128	coagulation factor II, thrombin	Homo sapiens	58-66	
15342215-8	2004	Augmented respiratory burst of neutrophils in response to thrombin-activated platelets was also inhibited by the two polyphenols as was neutrophil migration toward thrombin-induced supernatants of platelets.	Polyphenols	117-128	coagulation factor II, thrombin	Homo sapiens	164-172	
15342215-10	2004	Both polyphenols inhibited thrombin-induced MAPK, JNK and focal adhesion kinase activities in endothelial cells.	Polyphenols	5-16	coagulation factor II, thrombin	Homo sapiens	27-35	
15342215-12	2004	Moreover, the polyphenols protect endothelial adenosine nucleotide metabolism when downregulated by thrombin.	Polyphenols	14-25	coagulation factor II, thrombin	Homo sapiens	100-108