PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23210776-9	2013	The feasibility of PPs to prevent/ cure specific cutaneous toxicity connected to anti-EGFR therapy and to reduce multidrug resistance of skin tumors is also discussed.	Polyphenols	19-22	epidermal growth factor receptor	Homo sapiens	86-90	
21967610-0	2012	Plant polyphenols regulate chemokine expression and tissue repair in human keratinocytes through interaction with cytoplasmic and nuclear components of epidermal growth factor receptor system.	Polyphenols	6-17	epidermal growth factor receptor	Homo sapiens	152-184	
21756928-0	2011	Plant polyphenols differentially modulate inflammatory responses of human keratinocytes by interfering with activation of transcription factors NFkappaB and AhR and EGFR-ERK pathway.	Polyphenols	6-17	epidermal growth factor receptor	Homo sapiens	165-169	
15759309-3	2005	The protein tyrosine kinase activity of an EGFR preparation was effectively inhibited by the polyphenol-rich apple juice extract.	Polyphenols	93-103	epidermal growth factor receptor	Homo sapiens	43-47	
17427262-0	2007	Apple polyphenols diminish the phosphorylation of the epidermal growth factor receptor in HT29 colon carcinoma cells.	Polyphenols	6-17	epidermal growth factor receptor	Homo sapiens	54-86	
16404708-4	2006	The experimental data indicated that the molecular mechanisms of fatty acid synthase gene suppression by tea polyphenols (EGCG, theaflavins) may invite down-regulation of EGFR/PI3K/Akt/Sp-1 signal transduction pathways.	Polyphenols	109-120	epidermal growth factor receptor	Homo sapiens	171-175	
15759309-6	2005	However, as to be expected from the final concentration of these potential EGFR inhibitors in the original polyphenol-rich extract, a synthetic mixture of the apple juice constituents identified and available so far, including both proanthocyanidins and the quercetin glycosides, showed only marginal inhibitory effects on the EGFR.	Polyphenols	107-117	epidermal growth factor receptor	Homo sapiens	75-79	
15759309-7	2005	These results permit the assumption that yet unknown constituents contribute substantially to the potent EGFR-inhibitory properties of polyphenol-rich apple juice extract.	Polyphenols	135-145	epidermal growth factor receptor	Homo sapiens	105-109	
31223050-1	2019	Epigallocatechin gallate (EGCG) is a major polyphenols of green tea may have the possibility to inhibit epidermal growth factor receptor (EGFR) activity and lead to reduce non-small cell lung cancer (NSCLC) progression.	Polyphenols	43-54	epidermal growth factor receptor	Homo sapiens	104-136	
12494882-6	2002	Additionally, tea polyphenols inhibit the activities of many tumor-associated protein kinases, including epidermal growth factor receptor, vascular endothelial growth factor receptor, platelet-derived growth factor receptor, mitogen-activated protein kinase, and IkB kinase.	Polyphenols	18-29	epidermal growth factor receptor	Homo sapiens	105-137	
32951435-5	2022	Polyphenols are postulated to interact with lipid rafts in two ways: first, they interfere with the structural integrity of lipid rafts, by disrupting their structure and clustering of the ordered domains; second, they modulate the downstream signaling pathways mediated by lipid rafts, by binding to receptor proteins associated with lipid rafts, such as the 67 kDa laminin receptor (67LR), epidermal growth factor receptor (EGFR), and others.	Polyphenols	0-11	epidermal growth factor receptor	Homo sapiens	392-424	
32951435-5	2022	Polyphenols are postulated to interact with lipid rafts in two ways: first, they interfere with the structural integrity of lipid rafts, by disrupting their structure and clustering of the ordered domains; second, they modulate the downstream signaling pathways mediated by lipid rafts, by binding to receptor proteins associated with lipid rafts, such as the 67 kDa laminin receptor (67LR), epidermal growth factor receptor (EGFR), and others.	Polyphenols	0-11	epidermal growth factor receptor	Homo sapiens	426-430	
10223207-1	1999	Previous studies in our laboratory have shown that the major green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), suppressed autophosphorylation of epidermal growth factor (EGF) receptor induced by EGF in human A431 epidermoid carcinoma cells.	Polyphenols	71-81	epidermal growth factor receptor	Homo sapiens	156-194	
31223050-1	2019	Epigallocatechin gallate (EGCG) is a major polyphenols of green tea may have the possibility to inhibit epidermal growth factor receptor (EGFR) activity and lead to reduce non-small cell lung cancer (NSCLC) progression.	Polyphenols	43-54	epidermal growth factor receptor	Homo sapiens	138-142	
28432554-3	2017	However, in the presence of epigallocatechin-3-gallate (EGCG), a polyphenol in green tea, BEAS-2B cells resisted LPS-induced apoptosis and restored the expression of GRP and its downstream effectors such as epidermal growth factor receptor and NF-kappaB, as analysed by immunoblotting and qPCR.	Polyphenols	65-75	epidermal growth factor receptor	Homo sapiens	207-239