PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24630969-8 2014 At the same time, tea polyphenol pretreatment attenuated the increased level of serum IL-1beta, IL-6, ICAM-1 and TNF-alpha, and enhanced IL-10 production in RIRI rats. Polyphenols 22-32 tumor necrosis factor Rattus norvegicus 113-122 25431018-4 2015 Moreover, polyphenols, polysaccharides, or caffeine can improve blood lipid and antioxidant levels, and effectively reduce rat serum leptin levels, inhibit the absorption of fatty acids, and markedly reduce the expression levels of the IL-6 and TNF-alpha gene. Polyphenols 10-21 tumor necrosis factor Rattus norvegicus 245-254 16698588-0 2006 Tea polyphenols inhibit expressions of iNOS and TNF-alpha and prevent lipopolysaccharide-induced liver injury in rats. Polyphenols 4-15 tumor necrosis factor Rattus norvegicus 48-57 23186731-0 2013 Cocoa polyphenols prevent inflammation in the colon of azoxymethane-treated rats and in TNF-alpha-stimulated Caco-2 cells. Polyphenols 6-17 tumor necrosis factor Rattus norvegicus 88-97 23186731-9 2013 Additionally, the experiments in Caco-2 cells confirm that cocoa polyphenols effectively down-regulate the levels of inflammatory markers induced by TNF-alpha by inhibiting NF-kappaB translocation and JNK phosphorylation. Polyphenols 65-76 tumor necrosis factor Rattus norvegicus 149-158 16698588-9 2006 Pretreatment with tea polyphenols attenuated LPS-induced liver injury, and blunted the rises of serum TNF-alpha levels and lipid peroxidation and the induction of expressions of TNF-alpha, iNOS in the liver. Polyphenols 22-33 tumor necrosis factor Rattus norvegicus 102-111 16698588-9 2006 Pretreatment with tea polyphenols attenuated LPS-induced liver injury, and blunted the rises of serum TNF-alpha levels and lipid peroxidation and the induction of expressions of TNF-alpha, iNOS in the liver. Polyphenols 22-33 tumor necrosis factor Rattus norvegicus 178-187 16698588-10 2006 CONCLUSION: Tea polyphenols prevent LPS-induced liver injury, and the mechanisms may involve the reduction of serum TNF-alpha levels and lipid peroxidation and the suppression of TNF-alpha, iNOS expressions in the liver. Polyphenols 16-27 tumor necrosis factor Rattus norvegicus 116-125 16698588-10 2006 CONCLUSION: Tea polyphenols prevent LPS-induced liver injury, and the mechanisms may involve the reduction of serum TNF-alpha levels and lipid peroxidation and the suppression of TNF-alpha, iNOS expressions in the liver. Polyphenols 16-27 tumor necrosis factor Rattus norvegicus 179-188 34413929-7 2021 The supplement with 0.2 g/L tea polyphenols in the drinking water also had a good effect in alleviating the heat stress damage of the myocardial cells of hens at 38 C. Accordingly, light pathological lesions and downregulation of the myocardial injury-related indicators (LDH, CK, CK-MB, and TNF-alpha) were shown. Polyphenols 32-43 tumor necrosis factor Rattus norvegicus 292-301 11502884-2 2001 We previously showed that green tea polyphenols inhibited endotoxin-mediated tumor necrosis factor-alpha (TNF alpha) production by blocking NF-kappa B activation. Polyphenols 36-47 tumor necrosis factor Rattus norvegicus 106-115 11502884-5 2001 IEC-6 cells pretreated with an extract of green tea polyphenols (GrTPs; 0--0.4 mg/ml) had diminished TNF alpha-induced IKK and NF-kappa B activity. Polyphenols 52-63 tumor necrosis factor Rattus norvegicus 101-110 28659745-8 2017 Interestingly, dietary tea polyphenols decreased the serum levels of pro-inflammatory factors (TNF-alpha: 13%, p < 0.05; IL-1beta: 10%, p < 0.05; and IL-6: 48%, p < 0.05) and shifted the serum IL-10/TNF-alpha ratio to a predominantly anti-inflammatory milieu (0.52 +- 0.07 vs. 0.67 +- 0.10, p < 0.01). Polyphenols 27-38 tumor necrosis factor Rattus norvegicus 95-104 33516071-0 2021 Tea polyphenols and Levofloxacin alleviate the lung injury of hepatopulmonary syndrome in common bile duct ligation rats through Endotoxin -TNF signaling. Polyphenols 4-15 tumor necrosis factor Rattus norvegicus 140-143 33871312-0 2021 Combination of tea polyphenols and proanthocyanidins prevents menopause-related memory decline in rats via increased hippocampal synaptic plasticity by inhibiting p38 MAPK and TNF-alpha pathway. Polyphenols 19-30 tumor necrosis factor Rattus norvegicus 176-185 31817413-0 2019 Anti-Atherosclerotic Effect of Hibiscus Leaf Polyphenols against Tumor Necrosis Factor-alpha-Induced Abnormal Vascular Smooth Muscle Cell Migration and Proliferation. Polyphenols 45-56 tumor necrosis factor Rattus norvegicus 65-92 33084700-0 2020 Nelumbo nucifera leaf polyphenol extract and gallic acid inhibit TNF-alpha-induced vascular smooth muscle cell proliferation and migration involving the regulation of miR-21, miR-143 and miR-145. Polyphenols 22-32 tumor necrosis factor Rattus norvegicus 65-74 31533201-5 2019 The results show that pretreatments with honey polyphenols significantly improve SOD, GSH-Px, NO, and MPO levels and reduce DSS-induced colonic apoptosis, the colonic inflammatory cytokines IL-6, TNF-alpha, and TGF-beta1 accompanied by downregulation of IL-1beta, IL-6, TNF-alpha, and IFN-gamma gene and upregulation of IkappaB-alpha gene. Polyphenols 47-58 tumor necrosis factor Rattus norvegicus 196-205 31533201-5 2019 The results show that pretreatments with honey polyphenols significantly improve SOD, GSH-Px, NO, and MPO levels and reduce DSS-induced colonic apoptosis, the colonic inflammatory cytokines IL-6, TNF-alpha, and TGF-beta1 accompanied by downregulation of IL-1beta, IL-6, TNF-alpha, and IFN-gamma gene and upregulation of IkappaB-alpha gene. Polyphenols 47-58 tumor necrosis factor Rattus norvegicus 270-279 28659745-8 2017 Interestingly, dietary tea polyphenols decreased the serum levels of pro-inflammatory factors (TNF-alpha: 13%, p < 0.05; IL-1beta: 10%, p < 0.05; and IL-6: 48%, p < 0.05) and shifted the serum IL-10/TNF-alpha ratio to a predominantly anti-inflammatory milieu (0.52 +- 0.07 vs. 0.67 +- 0.10, p < 0.01). Polyphenols 27-38 tumor necrosis factor Rattus norvegicus 208-217