PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22347413-3 2012 Interestingly, tea polyphenols could substantially reduce IGF1 and increase IGFBP3. Polyphenols 19-30 insulin like growth factor 1 Homo sapiens 58-62 11756245-0 2002 Black tea polyphenols inhibit IGF-I-induced signaling through Akt in normal prostate epithelial cells and Du145 prostate carcinoma cells. Polyphenols 10-21 insulin like growth factor 1 Homo sapiens 30-35 11756245-5 2002 Pre-treatment of PrEC and Du145 cells with doses as low as 20 microg/ml of a mixture of black tea polyphenols (BTP) substantially reduced IGF-I-mediated Akt phosphorylation. Polyphenols 98-109 insulin like growth factor 1 Homo sapiens 138-143 11756245-8 2002 Our results indicate that polyphenols from black tea inhibit the IGF-I signal transduction pathway, which has been linked to increased prostate cancer incidence in human populations and, therefore, provide further support for the potential of BTP to prevent prostate cancer. Polyphenols 26-37 insulin like growth factor 1 Homo sapiens 65-70