PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33443209-5 2020 Overexpressing constitutively active Akt1 in SH-SY5Y cells or culturing cells with chlorogenic acid (a polyphenol found in coffee that activates Akt1) stimulated the CREB-dependent transcriptional activation of the gene encoding the E3 ubiquitin ligase RNF146. Polyphenols 103-113 ring finger protein 146 Homo sapiens 253-259