PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32768883-0	2020	Lychee seed polyphenol inhibits Abeta-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction.	Polyphenols	12-22	amyloid beta (A4) precursor protein	Mus musculus	32-37	
32768883-3	2020	In addition, we have previously reported that an active lychee seed fraction enriching polyphenol (LSP) exhibits anti-neuroinflammation in Abeta-induced BV-2 cells.	Polyphenols	87-97	amyloid beta (A4) precursor protein	Mus musculus	139-144	
32662804-6	2020	One promising polyphenol compound that has found application in this area is curcumin due to its natural binding affinity to Abeta fibrils and oligomers while giving out a strong fluorescence signal.	Polyphenols	14-24	amyloid beta (A4) precursor protein	Mus musculus	125-130	
16624814-1	2006	Recently, we have shown that green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) exerts a beneficial role on reducing brain Abeta levels, resulting in mitigation of cerebral amyloidosis in a mouse model of Alzheimer disease.	Polyphenols	39-49	amyloid beta (A4) precursor protein	Mus musculus	131-136	
26836197-9	2016	These findings justified the concept that polyphenol-mediated modulation of LDLR expression might serve as a safe and efficient disease-modifying therapy for AD by accelerating Abeta clearance.	Polyphenols	42-52	amyloid beta (A4) precursor protein	Mus musculus	177-182	
23468550-10	2013	Cell culture experiments verified that 2 polyphenol components of pomegranate extract, punicalagin and ellagic acid, attenuated NFAT activity in a reporter cell line (P < 0.05) and decreased Abeta-stimulated TNF-alpha secretion by murine microglia (P < 0.05).	Polyphenols	41-51	amyloid beta (A4) precursor protein	Mus musculus	191-196	
19125328-7	2009	The author reviews the studies on the protecting effects of natural antioxidants on neurons in neurodegenerative diseases, especially summarized the results about protective effect of green tea polyphenols on neurons against apoptosis of cellular and animal PD models, and of genestine and nicotine on neurons against A beta-induced apoptosis of hippocampal neuronal and transgenic mouse AD models.	Polyphenols	194-205	amyloid beta (A4) precursor protein	Mus musculus	318-324	
19384583-1	2009	Polyphenols extracted from grape seeds are able to inhibit amyloid-beta (Abeta) aggregation, reduce Abeta production and protect against Abeta neurotoxicity in vitro.	Polyphenols	0-11	amyloid beta (A4) precursor protein	Mus musculus	73-78	
19384583-1	2009	Polyphenols extracted from grape seeds are able to inhibit amyloid-beta (Abeta) aggregation, reduce Abeta production and protect against Abeta neurotoxicity in vitro.	Polyphenols	0-11	amyloid beta (A4) precursor protein	Mus musculus	100-105	
19384583-9	2009	Conclusively, polyphenol-rich GSE prevents the Abeta deposition and attenuates the inflammation in the brain of a transgenic mouse model, and this thus is promising in delaying development of AD.	Polyphenols	14-24	amyloid beta (A4) precursor protein	Mus musculus	47-52	
31213631-1	2019	A new mechanism is revealed by which a polyphenol, rosmarinic acid (RA), suppresses amyloid beta (Abeta) accumulation in mice.	Polyphenols	39-49	amyloid beta (A4) precursor protein	Mus musculus	98-103