PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18482975-3 2008 Here we show that polyphenols, including resveratrol and the synthetic polyphenol S17834, increase SIRT1 deacetylase activity, LKB1 phosphorylation at Ser(428), and AMPK activity. Polyphenols 18-29 serine/threonine kinase 11 Homo sapiens 127-131 35351574-16 2022 CONCLUSION: These results suggest that DI-HET is effective against NAFLD by activation of the SIRT-1/p-LKB-1/AMPK signaling pathway via polyphenols present in the extract. Polyphenols 136-147 serine/threonine kinase 11 Homo sapiens 103-108 18482975-3 2008 Here we show that polyphenols, including resveratrol and the synthetic polyphenol S17834, increase SIRT1 deacetylase activity, LKB1 phosphorylation at Ser(428), and AMPK activity. Polyphenols 18-28 serine/threonine kinase 11 Homo sapiens 127-131 18482975-8 2008 Moreover, LKB1, but not CaMKKbeta, is required for activation of AMPK by polyphenols and SIRT1. Polyphenols 73-84 serine/threonine kinase 11 Homo sapiens 10-14 18482975-10 2008 Targeting SIRT1/LKB1/AMPK signaling by polyphenols may have potential therapeutic implications for dyslipidemia and accelerated atherosclerosis in diabetes and age-related diseases. Polyphenols 39-50 serine/threonine kinase 11 Homo sapiens 16-20