PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29068698-5	2017	Furthermore, polyphenols exhibit anti-inflammatory activity on many levels via NF-kappaB inhibition, and MAPK, iNOS, and growth factors regulation.	Polyphenols	13-24	nitric oxide synthase 2	Homo sapiens	111-115	
25139172-4	2015	In general terms, non-flavonoid polyphenols reduce the production of inflammatory mediators, such as IL-1beta, IL-8, MCP-1, COX-2 or iNOS in these animal models of diabetes.	Polyphenols	32-43	nitric oxide synthase 2	Homo sapiens	133-137	
32655263-6	2020	We found that polyphenols and particularly flavonoids are able to markedly attenuate NO production and iNOS expression through the nuclear factor kappaB (NF-kappaB) and JAK/STAT signaling pathways.	Polyphenols	14-25	nitric oxide synthase 2	Homo sapiens	103-107	
26538333-0	2016	Extractable and non-extractable polyphenols from blueberries modulate LPS-induced expression of iNOS and COX-2 in RAW264.7 macrophages via the NF-kappaB signalling pathway.	Polyphenols	32-43	nitric oxide synthase 2	Homo sapiens	96-100	
15203283-1	2004	We recently reported that resveratrol, a grape-derived polyphenol, in vitro induces the apoptosis of leukemic B-cells and simultaneously inhibits the production of endogenous nitric oxide (NO) through inducible NO synthase (iNOS) down-regulation.	Polyphenols	55-65	nitric oxide synthase 2	Homo sapiens	201-222	
15033756-0	2003	The inducible NO synthase is downregulated during apoptosis of malignant cells from B-cell chronic lymphocytic leukemia induced by flavopiridol and polyphenols.	Polyphenols	148-159	nitric oxide synthase 2	Homo sapiens	4-25	
15033756-1	2003	Downregulation of iNOS and NO is a pathway common for flavones and polyphenols, two distinct families of phytoalexins.	Polyphenols	67-78	nitric oxide synthase 2	Homo sapiens	18-22	
12481898-8	2002	Polyphenol-driven apoptosis in chronic leukemic B cells was shown to correlate with an activation of caspase 3, a drop in the mitochondrial transmembrane potential, a reduction in the expression of the anti-apoptotic protein bcl-2, as well as a reduction in the expression of the inducible nitric oxide synthase (iNOS).	Polyphenols	0-10	nitric oxide synthase 2	Homo sapiens	280-311	
12481898-8	2002	Polyphenol-driven apoptosis in chronic leukemic B cells was shown to correlate with an activation of caspase 3, a drop in the mitochondrial transmembrane potential, a reduction in the expression of the anti-apoptotic protein bcl-2, as well as a reduction in the expression of the inducible nitric oxide synthase (iNOS).	Polyphenols	0-10	nitric oxide synthase 2	Homo sapiens	313-317	
9281609-2	1997	We investigated the effect of various tea polyphenols and caffeine on the induction of NO synthase (NOS) in thioglycollate-elicited and lipopolysaccharide (LPS)-activated peritoneal macrophages.	Polyphenols	42-53	nitric oxide synthase 2	Homo sapiens	87-98