PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27589705-0	2016	Red Grape Skin Polyphenols Blunt Matrix Metalloproteinase-2 and -9 Activity and Expression in Cell Models of Vascular Inflammation: Protective Role in Degenerative and Inflammatory Diseases.	Polyphenols	15-26	matrix metallopeptidase 2	Homo sapiens	33-66	
29230268-0	2017	An Alginate/Cyclodextrin Spray Drying Matrix to Improve Shelf Life and Antioxidant Efficiency of a Blood Orange By-Product Extract Rich in Polyphenols: MMPs Inhibition and Antiglycation Activity in Dysmetabolic Diseases.	Polyphenols	139-150	matrix metallopeptidase 2	Homo sapiens	152-156	
24481780-2	2015	In the present study, we demonstrate that green tea polyphenols (GTP) and its major constituent, epigallocatechin-3-gallate (EGCG) mediate epigenetic induction of TIMP-3 levels and play a key role in suppressing invasiveness and gelatinolytic activity of MMP-2 and MMP-9 in breast cancer cells.	Polyphenols	52-63	matrix metallopeptidase 2	Homo sapiens	255-260	
27231728-1	2016	The aim of the study was to investigate the effect of selected polyphenols: gallic acid (GA) and epigallocatechin gallate (EGCG) on matrix metalloproteinase (MMP-2 and MMP-9) activity in multidrug resistant (MDR) human breast adenocarcinoma cells: MCF7/DOX cells and obtained recently in our laboratory MCF7/DOX500 cells by the permanent selection of MCF7/DOX cells with 500 nM doxorubicin (DOX).	Polyphenols	63-74	matrix metallopeptidase 2	Homo sapiens	158-163	
20528747-0	2010	Black tea polyphenol (theaflavin) downregulates MMP-2 in human melanoma cell line A375 by involving multiple regulatory molecules.	Polyphenols	10-20	matrix metallopeptidase 2	Homo sapiens	48-53	
22082235-3	2011	This study showed that epigallocatechin-3-gallate (EGCG), a natural polyphenol in green tea, is a potent inhibitor of MMP-2 expression.	Polyphenols	68-78	matrix metallopeptidase 2	Homo sapiens	118-123	
22522122-7	2012	Interestingly, these polyphenols also modulated the expression of IL-6 signal transducing receptor (IL-6Ralpha) and the secretion of the extracellular matrix degrading enzyme MMP-2 as well as the expression of suppressor of cytokine signaling (SOCS3) protein.	Polyphenols	21-32	matrix metallopeptidase 2	Homo sapiens	175-180	
15823585-0	2005	Suppression of tumor cell invasiveness by hydrolyzable tannins (plant polyphenols) via the inhibition of matrix metalloproteinase-2/-9 activity.	Polyphenols	70-81	matrix metallopeptidase 2	Homo sapiens	105-134	
20021964-0	2009	[High glucose and tea polyphenols on expression of matrix metalloproteinase-2 and extracellular matrix metalloproteinase inducer in human umbilical vein endothelial cells].	Polyphenols	22-33	matrix metallopeptidase 2	Homo sapiens	51-77	
15885676-5	2005	The thrombin-induced activation of secreted MMP-2 was abolished by GTE and the green tea polyphenols (-)-epigallocatechin-3-gallate (EGCG) and (-)-epicatechin-3-gallate (ECG).	Polyphenols	89-100	matrix metallopeptidase 2	Homo sapiens	44-49	
16084102-1	2005	A series of compounds combining the beta-lactam and polyphenol scaffold have been prepared and evaluated for inhibition of human leukocyte elastase and matrix metallo-proteases MMP-2 and MMP-9.	Polyphenols	52-62	matrix metallopeptidase 2	Homo sapiens	177-182