PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28833446-1 2018 In this study, it was aimed to determine the doses of 4-methylcatechol causing cell death in rat insulinoma beta-cells (INS-1), to find out the type of cellular death at these doses, and to investigate the molecular mechanism of cellular death occurring. 4-methylcatechol 54-70 insulin 1 Rattus norvegicus 120-125 29473434-0 2018 4-Methylcatechol stimulates apoptosis and reduces insulin secretion by decreasing betacellulin and inhibin beta-A in INS-1 beta-cells. 4-methylcatechol 0-16 insulin 1 Rattus norvegicus 117-122 29473434-3 2018 The aim of this study was to determine the applying doses of 4-methylcatechol (4-MC) for triggening cell death and decreasing the cell function of rat insulinoma INS-1 beta cells. 4-methylcatechol 61-77 insulin 1 Rattus norvegicus 162-167 29473434-3 2018 The aim of this study was to determine the applying doses of 4-methylcatechol (4-MC) for triggening cell death and decreasing the cell function of rat insulinoma INS-1 beta cells. 4-methylcatechol 79-83 insulin 1 Rattus norvegicus 162-167 29473434-10 2018 Insulin secretion levels increased in INS-1 cells given 4-MC by basal glucose concentration while they did not response to high concentration of glucose, which indicates that 4-MC disrupts the functionality of INS-1 cells. 4-methylcatechol 56-60 insulin 1 Rattus norvegicus 38-43 29473434-10 2018 Insulin secretion levels increased in INS-1 cells given 4-MC by basal glucose concentration while they did not response to high concentration of glucose, which indicates that 4-MC disrupts the functionality of INS-1 cells. 4-methylcatechol 175-179 insulin 1 Rattus norvegicus 38-43 29473434-10 2018 Insulin secretion levels increased in INS-1 cells given 4-MC by basal glucose concentration while they did not response to high concentration of glucose, which indicates that 4-MC disrupts the functionality of INS-1 cells. 4-methylcatechol 175-179 insulin 1 Rattus norvegicus 210-215 29473434-11 2018 These results revealed that 4-MC induces apoptosis and decreases insulin secretion by reducing BTC and inhibin beta-A in insulinoma INS-1 cells. 4-methylcatechol 28-32 insulin 1 Rattus norvegicus 132-137