PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31554962-0	2020	Icariside II inhibits lipopolysaccharide-induced inflammation and amyloid production in rat astrocytes by regulating IKK/IkappaB/NF-kappaB/BACE1 signaling pathway.	baohuoside I	0-12	beta-secretase 1	Rattus norvegicus	139-144	
31554962-5	2020	Moreover, ICS II not only exerted the inhibitory effect on LPS-induced IkappaB-alpha degradation and NF-kappaB activation, but also decreased the levels of Abeta1-40, Abeta1-42, amyloid precursor protein (APP) and beta secretase 1 (BACE1) in the astrocytes.	baohuoside I	10-16	beta-secretase 1	Rattus norvegicus	214-230	
31554962-5	2020	Moreover, ICS II not only exerted the inhibitory effect on LPS-induced IkappaB-alpha degradation and NF-kappaB activation, but also decreased the levels of Abeta1-40, Abeta1-42, amyloid precursor protein (APP) and beta secretase 1 (BACE1) in the astrocytes.	baohuoside I	10-16	beta-secretase 1	Rattus norvegicus	232-237	
31554962-6	2020	Interestingly, molecular docking revealed that ICS II might directly bind to BACE1.	baohuoside I	47-53	beta-secretase 1	Rattus norvegicus	77-82