PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24917121-5	2014	The thieno[2,3-d]pyrimidine derivatives 16a-d showed potent HER2 enzyme inhibition and anti-proliferative activity against SK-BR-3 cells.	thieno(2,3-d)pyrimidine	4-27	erb-b2 receptor tyrosine kinase 2	Homo sapiens	60-64	
32698751-3	2021	It has been found that some thieno[2,3-d]pyrimidines exhibit better inhibitory activity against epidermal growth factor receptor (EGFR/ErbB-2) tyrosine kinase in comparison to aminoquinazolines.	thieno(2,3-d)pyrimidine	28-52	erb-b2 receptor tyrosine kinase 2	Homo sapiens	135-141	
29902719-0	2018	Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitors.	thieno(2,3-d)pyrimidine	78-101	erb-b2 receptor tyrosine kinase 2	Homo sapiens	118-122	
31051400-0	2019	Design, synthesis and anticancer evaluation of thieno[2,3-d]pyrimidine derivatives as dual EGFR/HER2 inhibitors and apoptosis inducers.	thieno(2,3-d)pyrimidine	47-70	erb-b2 receptor tyrosine kinase 2	Homo sapiens	96-100	
31051400-2	2019	In this study, we have designed and synthesized a series of thieno[2,3-d]pyrimidine derivatives as an EGFR and HER2 tyrosine kinase inhibitors.	thieno(2,3-d)pyrimidine	60-83	erb-b2 receptor tyrosine kinase 2	Homo sapiens	111-115