PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29876543-1 2018 We demonstrated a feasible method for providing polyrotaxanes (PRxs) with a controlled threading ratio of cyclic molecules and chain length of linear polymers by extending the linear polymers in the pseudo-PRx. Rotaxanes 48-61 periaxin Homo sapiens 63-66 28144361-4 2016 By this method, two series of azide group-terminated polyrotaxanes (benzylazide: PRX-Bn-N3, phenylazide: PRX-Ph-N3,) were synthesized for functionalization via click reactions. Rotaxanes 53-66 periaxin Homo sapiens 81-84 28144361-4 2016 By this method, two series of azide group-terminated polyrotaxanes (benzylazide: PRX-Bn-N3, phenylazide: PRX-Ph-N3,) were synthesized for functionalization via click reactions. Rotaxanes 53-66 periaxin Homo sapiens 105-108 25923376-1 2015 We have developed cationic polyrotaxanes composed of N,N-dimethylaminoethyl (DMAE) group-modified alpha-cyclodextrins (alpha-CDs) threaded along a poly(ethylene glycol) (PEG) chain capped with a terminal bulky stopper (DMAE-PRX) for the intracellular delivery of proteins through the polyelectrolyte complexation. Rotaxanes 27-40 periaxin Homo sapiens 224-227 32261169-1 2013 Acid-degradable cationic polyrotaxanes (PRXs) composed of N,N-dimethylaminoethyl (DMAE) group-modified alpha-cyclodextrins (CDs) that were threaded onto a poly(ethylene glycol) capped with a bulky stopper via acid-cleavable 3-sulfanylpropionyl ester linkages (DMAE-COO-PRX) were developed for improving the cytoplasmic transportation of PRX/siRNA polyplexes. Rotaxanes 25-38 periaxin Homo sapiens 40-43 22386920-2 2012 We previously reported that, for condensed DNA particles, a close relationship exists between the efficiency of DNA release and transfection activity, when biocleavable polyrotaxanes (DMAE-SS-PRX), in which the cationic density can be easily controlled. Rotaxanes 169-182 periaxin Homo sapiens 192-195 23332177-1 2013 To achieve successful delivery of siRNA therapeutics, cytocleavable cationic polyrotaxanes (PRXs) composed of N,N-dimethylaminoethyl (DMAE) group-modified alpha-cyclodextrins (CDs) that were threaded onto a poly(ethylene glycol) (PEG) axis and capped with a bulky stopper using cytocleavable disulfide linkages (DMAE-PRX) were utilized as an siRNA carrier. Rotaxanes 77-90 periaxin Homo sapiens 92-95