PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22714752-2	2012	OBJECTIVE: The objective of this study was to evaluate the profile of changes in alanine aminotransferase (ALT), aspartate aminotransferase (AST) and triglyceride levels in patients who had been treated with oral isotretinoin dispensed by the Sao Mateus/ES pharmacy for special drugs.	Isotretinoin	213-225	glutamic--pyruvic transaminase	Homo sapiens	81-105	
31498706-3	2021	Objective: The purpose of this study was to assess the management and clinical outcome of acne patients with abnormal aspartate transaminase (AST) and alanine aminotransferase (ALT) when receiving isotretinoin.	Isotretinoin	197-209	glutamic--pyruvic transaminase	Homo sapiens	151-175	
31380129-0	2019	Prolonged Serum Alanine Aminotransferase Elevation Associated with Isotretinoin Administration.	Isotretinoin	67-79	glutamic--pyruvic transaminase	Homo sapiens	16-40	
31380129-4	2019	We describe a 16-year-old male in whom alanine aminotransferase (ALT) rose from a baseline of 13 to 288 U/L after 20 weeks of treatment with 1.0-1.4 mg/kg of oral isotretinoin daily.	Isotretinoin	163-175	glutamic--pyruvic transaminase	Homo sapiens	39-63