PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16185265-9	2005	These data indicate that MMP and TIMP of epithelial origin may be involved in acne pathogenesis, and that isotretinoin-induced reduction in MMP-9 and -13 may contribute to the therapeutic effects of the agent in acne.	Isotretinoin	106-118	matrix metallopeptidase 9	Homo sapiens	140-145	
7625852-0	1995	Influence of aging, localization, glucocorticoids and isotretinoin on matrix metalloproteases 2 (MMP-2) and 9 (MMP-9) in suction blister fluids.	Isotretinoin	54-66	matrix metallopeptidase 9	Homo sapiens	111-116	
33730072-0	2021	Treatment of 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 inhibits TNF-alpha-mediated expression of MMP-9 protein and cell invasion through the suppression of JNK pathway and microRNA 221 in human pancreatic adenocarcinoma cancer cells.	Isotretinoin	13-33	matrix metallopeptidase 9	Homo sapiens	105-110	
34340266-1	2021	Aims: to evaluate changes in clinical periodontal parameters, salivary levels of MMP-8 and MMP-9, in individuals taking Isotretinoin (INN), and compare with individuals not taking the medication and to compare findings among different stages of periodontal disease and healthy periodontium.	Isotretinoin	120-132	matrix metallopeptidase 9	Homo sapiens	91-96	
32982373-13	2020	GATA2, C4BPA, CCR5, DEFA3, ELANE, MMP9, and RPS4Y1 might be susceptible to genes that could participate in the ISO-induced aggravation of acne.	Isotretinoin	111-114	matrix metallopeptidase 9	Homo sapiens	34-38