PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1425698-7	1992	The inhibition of thioredoxin reductase activity by 13-cis-retinoic acid resulted in a decrease in the regeneration of glyceraldehyde-3-phosphate dehydrogenase in the H2O2-treated endothelial cells.	Isotretinoin	52-72	thioredoxin	Homo sapiens	18-29	
8555652-5	1995	Furthermore, inhibitors of TRX reductase, 13-cis-retinoic acid (13-cis-RA) and azelaic acid, inhibited the DNA synthesis of these cells.	Isotretinoin	64-73	thioredoxin	Homo sapiens	27-30	
1329444-6	1992	To clarify the role of ADF/thioredoxin system in the viral transformation, we tested the effect of 13-cis-retinoic acid (RA), which is a competitive inhibitor of thioredoxin reductase, on the growth of ADF high producing cells.	Isotretinoin	99-119	thioredoxin	Homo sapiens	202-205	
1329444-8	1992	RA dose-dependently reduced the cell number and viability of ADF high producing lymphoid cells.	Isotretinoin	0-2	thioredoxin	Homo sapiens	61-64	
1329444-10	1992	It is suggested that RA has an inhibitory effect on the activation and the growth of cells producing ADF and that inhibition of the ADF/thioredoxin system may be a new therapeutic approach for retrovirus-related disorders.	Isotretinoin	21-23	thioredoxin	Homo sapiens	101-104	
1329444-10	1992	It is suggested that RA has an inhibitory effect on the activation and the growth of cells producing ADF and that inhibition of the ADF/thioredoxin system may be a new therapeutic approach for retrovirus-related disorders.	Isotretinoin	21-23	thioredoxin	Homo sapiens	132-135	
1329444-10	1992	It is suggested that RA has an inhibitory effect on the activation and the growth of cells producing ADF and that inhibition of the ADF/thioredoxin system may be a new therapeutic approach for retrovirus-related disorders.	Isotretinoin	21-23	thioredoxin	Homo sapiens	136-147