PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31502400-0 2019 Cediranib phase-II study in children with metastatic alveolar soft-part sarcoma (ASPS). cediranib 0-9 ASPSCR1 tether for SLC2A4, UBX domain containing Homo sapiens 81-85 31502400-3 2019 In a phase-II trial of the VEGF receptor inhibitor cediranib for adults with ASPS, the partial response (PR) rate (response evaluation criteria in solid tumors [RECIST] v1.0) was 35% (15/43; 95% confidence interval: 21-51%). cediranib 51-60 ASPSCR1 tether for SLC2A4, UBX domain containing Homo sapiens 77-81 23630200-3 2013 PATIENTS AND METHODS: We conducted a phase II trial of once-daily cediranib (30 mg) given in 28-day cycles for patients with metastatic, unresectable ASPS to determine the objective response rate (ORR). cediranib 66-75 ASPSCR1 tether for SLC2A4, UBX domain containing Homo sapiens 150-154 23630200-9 2013 CONCLUSION: In this largest prospective trial to date of systemic therapy for metastatic ASPS, we observed that cediranib has substantial single-agent activity, producing an ORR of 35% and a disease control rate of 84% at 24 weeks. cediranib 112-121 ASPSCR1 tether for SLC2A4, UBX domain containing Homo sapiens 89-93 23630200-10 2013 On the basis of these results, an open-label, multicenter, randomized phase II registration trial is currently being conducted for patients with metastatic ASPS comparing cediranib with another VEGFR inhibitor, sunitinib. cediranib 171-180 ASPSCR1 tether for SLC2A4, UBX domain containing Homo sapiens 156-160