PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31092693-5 2019 This occurs partially as a result of cediranib inducing hypoxia, which suppresses expression of the HDR factors BRCA1/2 and RAD51 recombinase (RAD51). cediranib 37-46 RAD51 recombinase Homo sapiens 124-141 31182430-2 2019 Cediranib may confer sensitivity to olaparib by increasing tumor hypoxia and inhibiting platelet-derived growth factor receptor, which reduces BRCA1/2 and RAD51 expression, thus decreasing homology-deficient DNA repair. cediranib 0-9 RAD51 recombinase Homo sapiens 155-160 33742489-2 2021 BACKGROUND: Cediranib, a vascular endothelial growth factor receptor inhibitor, suppresses expression of BRCA1/2 and RAD51 inducing homologous recombination DNA repair deficiency (HRD) in several cancer cell lines and xenograft models [1]. cediranib 12-21 RAD51 recombinase Homo sapiens 117-122 31092693-5 2019 This occurs partially as a result of cediranib inducing hypoxia, which suppresses expression of the HDR factors BRCA1/2 and RAD51 recombinase (RAD51). cediranib 37-46 RAD51 recombinase Homo sapiens 124-129