PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28881718-0 2017 Quercetin inhibits Cr(VI)-induced malignant cell transformation by targeting miR-21-PDCD4 signaling pathway. chromium hexavalent ion 19-25 programmed cell death 4 Homo sapiens 84-89 31951899-0 2020 ROS-mediated miR-21-5p regulates the proliferation and apoptosis of Cr(VI)-exposed L02 hepatocytes via targeting PDCD4. chromium hexavalent ion 68-74 programmed cell death 4 Homo sapiens 113-118 31951899-10 2020 In conclusion, from the perspective of epigenetics, the present study revealed that ROS-mediated miR-21-5p regulated the proliferation and apoptosis of Cr(VI)-exposed L02 hepatocytes via targeting PDCD4, which provided the new targets for molecular intervention and treatment of liver damage in Cr(VI)-exposed population. chromium hexavalent ion 152-158 programmed cell death 4 Homo sapiens 197-202 31951899-10 2020 In conclusion, from the perspective of epigenetics, the present study revealed that ROS-mediated miR-21-5p regulated the proliferation and apoptosis of Cr(VI)-exposed L02 hepatocytes via targeting PDCD4, which provided the new targets for molecular intervention and treatment of liver damage in Cr(VI)-exposed population. chromium hexavalent ion 295-301 programmed cell death 4 Homo sapiens 197-202 27323401-12 2016 We also found an increased miR-21 level and decreased PDCD4 expression in xenograft tumors generated with chronic Cr(VI)-exposed BEAS-2B cells. chromium hexavalent ion 114-120 programmed cell death 4 Homo sapiens 54-59 27323401-14 2016 Taken together, these results demonstrate that the miR-21-PDCD4 signaling axis plays an important role in Cr(VI)-induced carcinogenesis. chromium hexavalent ion 106-112 programmed cell death 4 Homo sapiens 58-63 28881718-10 2017 Taken together, these results demonstrate that quercetin is able to protect BEAS-2B cells from Cr(VI)-induced carcinogenesis by targeting miR-21-PDCD4 signaling. chromium hexavalent ion 95-101 programmed cell death 4 Homo sapiens 145-150