PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11301049-2 2001 The presence of PGE(2) or the PGI(2) analog carbacyclin in the medium reduced the TNFalpha production to one-half, whereas IL-10 production increased several fold; and indomethacin caused the reverse effects, suggesting that endogenous prostaglandins may have a regulatory effect on the cytokine production. carboprostacyclin 44-55 tumor necrosis factor Mus musculus 82-90