PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25954880-3 2015 ITC measurements showed that the yeast PROPPIN family members Atg18, Atg21, and Hsv2 bind PtdIns3P and PtdIns(3,5)P2 with high affinities in the nanomolar to low-micromolar range and have two phosphoinositide (PIP)-binding sites. phosphatidylinositol 3,5-diphosphate 103-116 Atg21p Saccharomyces cerevisiae S288C 69-74