PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35488279-6 2022 In addition, our data showed that C5a increased the production of mitochondrial reactive oxygen species (ROS) and that the promotion of NET formation by C5a was mitochondrial ROS (Mito-ROS) dependent. mito-ros 180-188 hemolytic complement Mus musculus 34-37 35488279-6 2022 In addition, our data showed that C5a increased the production of mitochondrial reactive oxygen species (ROS) and that the promotion of NET formation by C5a was mitochondrial ROS (Mito-ROS) dependent. mito-ros 180-188 hemolytic complement Mus musculus 153-156 35488279-7 2022 Furthermore, we found that C5a induced the production of Mito-ROS by inhibiting mitochondrial STAT3 activity. mito-ros 57-65 hemolytic complement Mus musculus 27-30 35488279-8 2022 CONCLUSIONS: By inhibiting mitochondrial STAT3 to elicit Mito-ROS generation, C5a triggers the generation of NETs to promote the development of arterial thrombosis. mito-ros 57-65 hemolytic complement Mus musculus 78-81