PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18717335-0 2008 [Hydroxysafflor yellow A up-regulates HIF-1alpha via inhibition of VHL and p53 in Eahy 926 cell line exposed to hypoxia]. hydroxysafflor yellow A 1-24 hypoxia inducible factor 1 subunit alpha Homo sapiens 38-48 18670359-0 2008 Hydroxysafflor yellow A enhances survival of vascular endothelial cells under hypoxia via upregulation of the HIF-1 alpha-VEGF pathway and regulation of Bcl-2/Bax. hydroxysafflor yellow A 0-23 hypoxia inducible factor 1 subunit alpha Homo sapiens 110-121 18717335-1 2008 In present study, we investigated the mechanism of regulating HIF-1alpha expression by hydroxysafflor yellow A (HSYA) in Eahy 926 cell line under 1% O2 hypoxia. hydroxysafflor yellow A 87-110 hypoxia inducible factor 1 subunit alpha Homo sapiens 62-72 30338719-7 2018 The in vitro results showed that the combination of DFO and HSYA exerted synergistic effect on enhancing angiogenesis by upregulation of hypoxia inducible factor-1 alpha (HIF-1alpha) expression. hydroxysafflor yellow A 60-64 hypoxia inducible factor 1 subunit alpha Homo sapiens 137-169 30338719-7 2018 The in vitro results showed that the combination of DFO and HSYA exerted synergistic effect on enhancing angiogenesis by upregulation of hypoxia inducible factor-1 alpha (HIF-1alpha) expression. hydroxysafflor yellow A 60-64 hypoxia inducible factor 1 subunit alpha Homo sapiens 171-181