PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27260389-6 2016 Present data regarding a role for genes and proteins MGMT, IDH1/2, YB-1, MELK, MVP/LRP, MDR1 (ABCB1), and genes encoding other ABC transporters as well as Akt3 kinase in developing resistance of GBL to TMZ are discussed. Temozolomide 202-205 Y-box binding protein 1 Homo sapiens 59-71 19996271-0 2009 Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase. Temozolomide 100-112 Y-box binding protein 1 Homo sapiens 14-37 19996271-11 2009 Importantly, inhibiting YB-1 enhanced temozolomide sensitivity in a manner that was independent of MGMT in models of adult and pediatric GBM. Temozolomide 38-50 Y-box binding protein 1 Homo sapiens 24-28