PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29749469-0	2018	Association between SOX9 and CA9 in glioma, and its effects on chemosensitivity to TMZ.	Temozolomide	83-86	carbonic anhydrase 9	Homo sapiens	29-32	
29749469-11	2018	On the whole, the findings of this study establish the SOX9/CA9-mediated oncogenic pathway in glioma, the inhibition of which enhances the sensitivity of glioma cells to TMZ treatment, and thus highlights the value of developing small molecules or antibodies against the SOX9/CA9 pathway, for combination therapy with TMZ, in the more efficient management of glioma.	Temozolomide	170-173	carbonic anhydrase 9	Homo sapiens	60-63	
29749469-11	2018	On the whole, the findings of this study establish the SOX9/CA9-mediated oncogenic pathway in glioma, the inhibition of which enhances the sensitivity of glioma cells to TMZ treatment, and thus highlights the value of developing small molecules or antibodies against the SOX9/CA9 pathway, for combination therapy with TMZ, in the more efficient management of glioma.	Temozolomide	170-173	carbonic anhydrase 9	Homo sapiens	276-279	
29749469-11	2018	On the whole, the findings of this study establish the SOX9/CA9-mediated oncogenic pathway in glioma, the inhibition of which enhances the sensitivity of glioma cells to TMZ treatment, and thus highlights the value of developing small molecules or antibodies against the SOX9/CA9 pathway, for combination therapy with TMZ, in the more efficient management of glioma.	Temozolomide	318-321	carbonic anhydrase 9	Homo sapiens	60-63	
30362384-4	2019	Here, we demonstrate that the SLC-0111 CAIX inhibitor potentiates cytotoxicity of Dacarbazine and Temozolomide currently used for advanced melanoma treatment.	Temozolomide	98-110	carbonic anhydrase 9	Homo sapiens	39-43	
30426805-10	2018	CA IX/XII inhibitors are synergistic with other anticancer agents (cisplatin, proton pump inhibitors, doxorubicin, temozolamide) and are a versatile, emerging class of antitumor drugs.	Temozolomide	115-127	carbonic anhydrase 9	Homo sapiens	0-5	
29263302-0	2017	Addition of carbonic anhydrase 9 inhibitor SLC-0111 to temozolomide treatment delays glioblastoma growth in vivo.	Temozolomide	55-67	carbonic anhydrase 9	Homo sapiens	12-32	
29263302-3	2017	Temozolomide efficacy may be increased by targeting carbonic anhydrase 9 (CA9), a hypoxia-responsive gene important for maintaining the altered pH gradient of tumor cells.	Temozolomide	0-12	carbonic anhydrase 9	Homo sapiens	52-72	
29263302-3	2017	Temozolomide efficacy may be increased by targeting carbonic anhydrase 9 (CA9), a hypoxia-responsive gene important for maintaining the altered pH gradient of tumor cells.	Temozolomide	0-12	carbonic anhydrase 9	Homo sapiens	74-77