PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29048680-0 2017 miR-146b-5p suppresses glioblastoma cell resistance to temozolomide through targeting TRAF6. Temozolomide 55-67 TNF receptor associated factor 6 Homo sapiens 86-91 30571666-2 2019 In glioblastoma multiforme (GBM), TRAF6 depression by miRNA could decrease GBM cell resistance to temozolomide, but the prognostic values of TRAF6 and its functions in GBM progression have not been elucidated. Temozolomide 98-110 TNF receptor associated factor 6 Homo sapiens 34-39 29048680-11 2017 Collectively, our data demonstrated that miR-146b-5p, as a tumor suppressor, mediated temozolomide resistance in GBM cells through negatively regulating TRAF6 expression, indicating that miR-146b-5p and its targeted genes would be potential therapeutic targets for glioma therapy. Temozolomide 86-98 TNF receptor associated factor 6 Homo sapiens 153-158