PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32407821-6 2020 The TAAR1 agonist RO5263397 significantly decreased the expression of ethanol-induced behavioral sensitization both in male and female WT mice (0.1 mg/kg and 0.32 mg/kg). 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 18-27 trace amine-associated receptor 1 Mus musculus 4-9 33753244-6 2021 In addition, chronic treatment with the selective TAAR1 partial agonist RO5263397 ameliorated chronic stress-induced changes in cognitive function, dendritic arborization, and the synapse number of pyramidal neurons in the mPFC but did not affect chronic stress-induced anxiety-like behaviors. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 72-81 trace amine-associated receptor 1 Mus musculus 50-55 34291306-0 2021 The selective TAAR1 partial agonist RO5263397 promoted novelty recognition memory in mice. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 36-45 trace amine-associated receptor 1 Mus musculus 14-19 34291306-4 2021 OBJECTIVES: Here, by using the mice novel object recognition (NOR) test, we examined the effects of the selective TAAR1 partial agonist RO5263397 on recognition memory. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 136-145 trace amine-associated receptor 1 Mus musculus 114-119 34291306-6 2021 RO5263397 promoted the retrieval of STM in the wild-type (WT) littermates but not TAAR1-KO mice, indicating that the effects of RO5263397 were dependent on TAAR1. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 128-137 trace amine-associated receptor 1 Mus musculus 156-161 32407821-9 2020 CONCLUSIONS: These results indicated that the TAAR1 agonist RO5263397 negatively regulated the expression and development of ethanol-elicited behavioral sensitization in WT but not in TAAR1-KO mice. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 60-69 trace amine-associated receptor 1 Mus musculus 46-51 27919403-7 2017 The TAAR1 partial agonist RO5263397 also promoted wakefulness and suppressed nonrapid eye movement sleep. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 26-35 trace amine-associated receptor 1 Mus musculus 4-9 31503202-1 2019 The trace amine-associated receptor 1 (TAAR1) agonist RO5263397 effect on sensory gating in C57BL/6 mice was studied. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 54-63 trace amine-associated receptor 1 Mus musculus 4-37 31503202-1 2019 The trace amine-associated receptor 1 (TAAR1) agonist RO5263397 effect on sensory gating in C57BL/6 mice was studied. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 54-63 trace amine-associated receptor 1 Mus musculus 39-44 29977204-5 2018 Like other TAAR1 agonists, RO5263397 potently suppressed high dopamine-dependent hyperactivity in mice lacking the dopamine transporter. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 27-36 trace amine-associated receptor 1 Mus musculus 11-16 27658486-4 2017 Following a 24 h recording to characterize basal sleep/wake parameters, mice were sleep deprived (SD) for 6 h. In another experiment, mice were given three doses of the TAAR1 partial agonist RO5263397, caffeine, or vehicle p.o. 4-(3-fluoro-2-methylphenyl)-4,5-dihydrooxazol-2-ylamine 191-200 trace amine-associated receptor 1 Mus musculus 169-174