PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31653415-8 2020 In IRI mice models, vorapaxar treatment significantly decreased serum transaminase levels, improved liver histological damage, reduced the number of apoptotic cells as evaluated by terminal deoxynucleotidyl transferase dUTP nick end labeling staining (median: 135 versus 25, P = 0.004), and induced extracellular signal-regulated kinase 1/2 (ERK 1/2) cell survival signaling (phospho-ERK/total ERK 1/2: 0.96 versus 5.34, P = 0.004). vorapaxar 20-29 mitogen-activated protein kinase 1 Mus musculus 342-345 31653415-9 2020 Pretreatment of SECs with vorapaxar significantly attenuated apoptosis and induced phosphorylation of ERK 1/2 in vitro (phospho-ERK/total ERK 1/2: 0.66 versus 3.04, P = 0.009). vorapaxar 26-35 mitogen-activated protein kinase 1 Mus musculus 102-105