PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31895025-1 2019 OBJECTIVE: The aim of this study was to observe the impacts of the specific cyclooxygenase-2 inhibitor celecoxib on cardiac structures, functions, and inflammatory factors during the process of pressure overload-induced myocardial hypertrophy. celecoxib 103-112 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 76-92 31628940-2 2020 The current study aimed to explore the potential protective impacts of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on gentamicin-induced nephrotoxicity and the potential mechanisms in rats. celecoxib 71-80 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 94-110 31628940-2 2020 The current study aimed to explore the potential protective impacts of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on gentamicin-induced nephrotoxicity and the potential mechanisms in rats. celecoxib 71-80 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 112-117 31628940-7 2020 In immunohistochemistry, celecoxib-treated rats showed decreased immunoreactivity against COX-2 in tubular cells and a mild positive immunoreactivity against heat shock protein 70 (HSP70) in renal interstitial cells. celecoxib 25-34 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 90-95 31693705-2 2019 Using the selective inhibitors celecoxib and zaltoprofen, cyclooxygenase-2 has been shown to be involved in the initiation, but not the maintenance, of muscular mechanical hyperalgesia induced by lengthening contractions, which serves as a useful model for the study of myofascial pain syndrome. celecoxib 31-40 prostaglandin-endoperoxide synthase 2 Rattus norvegicus 58-74