PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26848751-6 2016 IL-1beta-induced the degradation of IkappaBalpha, and the phosphorylation of p38 and ERK, and the IL-1beta-induced expression of IL-8 mRNA was inhibited by specific inhibitors, such as BAY-117085 for NF-kB, SB203580 for p38, and PD98059 for ERK. BAY 11-7085 185-195 interleukin 1 beta Homo sapiens 0-8 26848751-6 2016 IL-1beta-induced the degradation of IkappaBalpha, and the phosphorylation of p38 and ERK, and the IL-1beta-induced expression of IL-8 mRNA was inhibited by specific inhibitors, such as BAY-117085 for NF-kB, SB203580 for p38, and PD98059 for ERK. BAY 11-7085 185-195 interleukin 1 beta Homo sapiens 98-106 20138154-4 2010 Hirsutenone, dexamethasone, ERK inhibitor or Bay 11-7085 (an inhibitor of NF-kappaB activation) reduced the lipopolysaccharide-induced production of cytokines IL-1beta and IL-8, and the chemokine CCL17. BAY 11-7085 45-56 interleukin 1 beta Homo sapiens 159-167 19135383-5 2009 We also found that IL-1beta-induced release of IL-8 from MH7A cells was completely blocked by pretreatment with the (IL-8) inhibitor Bay11-7085, indicating that activation of NF-kappaB signaling plays an important role in the secretion of IL-8. BAY 11-7085 133-143 interleukin 1 beta Homo sapiens 19-27 25971793-5 2015 Parthenolide, Akt inhibitor, Bay 11-7085, and N-acetylcysteine each attenuated the lipopolysaccharide-induced production of IL-1beta and PGE2, increase in the levels of cyclooxygenase, formation of reactive oxygen species, increase in the levels of Toll-like receptor-4, and activation of the Akt/mTOR and NF-kappaB in keratinocytes. BAY 11-7085 29-40 interleukin 1 beta Homo sapiens 124-132