PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19284778-3 2009 For one such hit class, defined by a central aminobenzylpiperidine (ABP) moiety, X-ray crystal structures of BACE mutant-disulfide conjugates revealed that the fragment bound by engaging both catalytic aspartates with hydrogen bonds. abp 68-71 beta-secretase 1 Homo sapiens 109-113