PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28489606-0 2017 Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response. Pantoprazole 0-12 signal transducer and activator of transcription 3 Mus musculus 29-34 28489606-9 2017 Our results indicated that pantoprazole treatment can decrease the levels of serum IL-6 and TNF-alpha (56.3% and 67.6%, respectively), and inhibit the activation of the JAK2/STAT3 signaling pathway. Pantoprazole 27-39 signal transducer and activator of transcription 3 Mus musculus 174-179 28489606-11 2017 CONCLUSION: Our findings suggested that pantoprazole can alleviate cancer cachexia skeletal muscle wasting by inhibiting the inflammatory response and blocking the JAK2/STAT3 or ubiquitin proteasome pathway. Pantoprazole 40-52 signal transducer and activator of transcription 3 Mus musculus 169-174