PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22151918-7 2012 RESULTS: Cucurbitacin B has significantly suppressed 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced cell invasion and migration in a concentration-dependent manner, which was accompanied with suppression of TPA-induced MMP-9 expression through inactivation of phosphorylation of extracellular signal-regulated kinase (ERK) 1/2, p38 and Akt. cucurbitacin B 11-25 matrix metallopeptidase 9 Homo sapiens 225-230 33507702-10 2021 Further molecular studies demonstrated that FAK inhibitor-14 and cucurbitacin B downregulated the expression of metastasis-associated proteins including MMP-9, ICAM-1 and VEGF. cucurbitacin B 65-79 matrix metallopeptidase 9 Homo sapiens 153-158 33507702-11 2021 Consequently, exposure to cucurbitacin B inhibited the production of MMP-9 enzyme in CCA cells similar to FAK inhibitor-14 treatment. cucurbitacin B 26-40 matrix metallopeptidase 9 Homo sapiens 69-74 22151918-9 2012 CONCLUSION: Cucurbitacin B has a potential value for suppressing metastasis of human hepatoma cells through suppressing the expression of MMP-9. cucurbitacin B 14-28 matrix metallopeptidase 9 Homo sapiens 140-145