PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17464174-5 2007 Activation of p38 MAPK and ERK1/2 was induced in both a time and dose-dependent manner after 9CRA stimulation. Alitretinoin 93-97 mitogen-activated protein kinase 3 Homo sapiens 27-33 17464174-6 2007 Both p38 MAPK and ERK1/2 phosphorylation peaked at 2 h after a 100 nM 9CRA treatment. Alitretinoin 70-74 mitogen-activated protein kinase 3 Homo sapiens 18-24 12807734-2 2003 On the other hand, HCCs become refractory to physiological concentrations of the natural RXRalpha-ligand, 9-cis retinoic acid (9cRA), due to extracellular signal-regulated kinase (Erk) 1/2-mediated phosphorylation and inactivation of RXRalpha. Alitretinoin 106-125 mitogen-activated protein kinase 3 Homo sapiens 141-188