PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21399653-0	2011	Involvement of estrogen receptor-beta in farrerol inhibition of rat thoracic aorta vascular smooth muscle cell proliferation.	farrerol	41-49	estrogen receptor 2	Rattus norvegicus	15-37	
21399653-8	2011	In receptor binding assays, farrerol inhibited the binding of [(3)H]estradiol for ERalpha and ERbeta with IC(50) values of 57 mumol/L and 2.7 mumol/L, respectively, implying that farrerol had a higher affinity for ERbeta.	farrerol	28-36	estrogen receptor 2	Rattus norvegicus	94-100	
21399653-8	2011	In receptor binding assays, farrerol inhibited the binding of [(3)H]estradiol for ERalpha and ERbeta with IC(50) values of 57 mumol/L and 2.7 mumol/L, respectively, implying that farrerol had a higher affinity for ERbeta.	farrerol	28-36	estrogen receptor 2	Rattus norvegicus	214-220	
21399653-8	2011	In receptor binding assays, farrerol inhibited the binding of [(3)H]estradiol for ERalpha and ERbeta with IC(50) values of 57 mumol/L and 2.7 mumol/L, respectively, implying that farrerol had a higher affinity for ERbeta.	farrerol	179-187	estrogen receptor 2	Rattus norvegicus	94-100	
21399653-8	2011	In receptor binding assays, farrerol inhibited the binding of [(3)H]estradiol for ERalpha and ERbeta with IC(50) values of 57 mumol/L and 2.7 mumol/L, respectively, implying that farrerol had a higher affinity for ERbeta.	farrerol	179-187	estrogen receptor 2	Rattus norvegicus	214-220	
21399653-9	2011	Finally, the inhibition of VSMC proliferation by farrerol (3 mumol/L) was abolished by the specific ERbeta antagonist PHTPP (5 mumol/L).	farrerol	49-57	estrogen receptor 2	Rattus norvegicus	100-106	
21399653-10	2011	CONCLUSION: Farrerol acts as a functional phytoestrogen to inhibit FBS-induced VSMC proliferation, mainly via interaction with ERbeta, which may be helpful in the treatment of cardiovascular diseases related to abnormal VSMCs proliferation.	farrerol	12-20	estrogen receptor 2	Rattus norvegicus	127-133