PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31838053-7 2020 We also found that restoration of Nox4 expression abolished the protective effects of farrerol on high glucose-induced proliferation and reactive oxygen species generation. farrerol 86-94 NADPH oxidase 4 Homo sapiens 34-38 31838053-8 2020 Furthermore, pretreatment with the Nox4 inhibitor diphenyliodonium or the ERK1/2 pathway inhibitor PD98059, displayed similar ameliorated effects of farrerol on high glucose-induced mesangial cell damage. farrerol 149-157 NADPH oxidase 4 Homo sapiens 35-39 31838053-9 2020 Taken together, these data suggest that farrerol displays protective effects on high glucose induced mesangial cell injury, partly through the Nox4-mediated ROS/ERK1/2 signaling pathway. farrerol 40-48 NADPH oxidase 4 Homo sapiens 143-147