PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32247733-0 2020 Synthesis of novel tryptanthrin derivatives as dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase. tryptanthrine 19-31 indoleamine 2,3-dioxygenase 1 Homo sapiens 66-95 32247733-3 2020 Natural product tryptanthrin has been confirmed to bear IDO1 and/or TDO inhibitory activities. tryptanthrine 16-28 indoleamine 2,3-dioxygenase 1 Homo sapiens 56-60 32247733-4 2020 Herein, twelve novel tryptanthrin derivatives were synthesized and evaluated for the IDO1 and TDO inhibitory potency. tryptanthrine 21-33 indoleamine 2,3-dioxygenase 1 Homo sapiens 85-89