PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29760046-5 2018 The radiosensitizing effects of CUDC-907 were mediated by decreased NFkappaB/Forkhead box M1 (FOXM1) recruitment to promoters of genes involved in the DNA damage response; exogenous expression of NFkappaB/FOXM1 protected from CUDC-907-induced cytotoxicity. CUDC-907 32-40 forkhead box M1 Homo sapiens 205-210 33069237-7 2020 RESULTS: CUDC-907 treatment downregulated MYC paralogs and FoxM1, induced G1 cell-cycle arrest, and impaired DNA double-strand break (DSB) repair capacity in SCLC cells, which produced a potent antiproliferative effect. CUDC-907 9-17 forkhead box M1 Homo sapiens 59-64 33069237-9 2020 Mechanistic investigations demonstrated that CUDC-907 synergized with olaparib through the blockade of DSB repair pathways and downregulation of MYC paralogs and FoxM1. CUDC-907 45-53 forkhead box M1 Homo sapiens 162-167 29760046-5 2018 The radiosensitizing effects of CUDC-907 were mediated by decreased NFkappaB/Forkhead box M1 (FOXM1) recruitment to promoters of genes involved in the DNA damage response; exogenous expression of NFkappaB/FOXM1 protected from CUDC-907-induced cytotoxicity. CUDC-907 32-40 forkhead box M1 Homo sapiens 77-92 29760046-5 2018 The radiosensitizing effects of CUDC-907 were mediated by decreased NFkappaB/Forkhead box M1 (FOXM1) recruitment to promoters of genes involved in the DNA damage response; exogenous expression of NFkappaB/FOXM1 protected from CUDC-907-induced cytotoxicity. CUDC-907 32-40 forkhead box M1 Homo sapiens 94-99