PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33000123-10	2021	RESULTS: From a kinase inhibitor library, we identified the dual PI3K/HDAC inhibitor CUDC-907 as a potent inhibitor of murine and human corticotroph tumor ACTH secretion (EC50 1-5nM), and cell proliferation (IC50 5nM).	CUDC-907	85-93	proopiomelanocortin	Homo sapiens	155-159	
33000123-12	2021	We also demonstrated that CUDC-907 acts through HDAC1/2 inhibition at the POMC transcriptional level combined with its PI3K-mediated inhibition of corticotroph cell viability to reduce ACTH secretion.	CUDC-907	26-34	proopiomelanocortin	Homo sapiens	74-78