PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14962699-11 2003 Treatment with IFN-alpha significantly increased the plasma cholesterol levels in both treated and untreated mice (mean 31.03+/-5.53 mmol/l vs. 24.91+/-6.03 mmol/l, respectively; p<0.022) as well as the plasma triglyceride levels (mean 4.79+/-1.57 mmol/l vs. 3.10+/-1.85 mmol/l, respectively; p<0.033). Cholesterol 60-71 interferon alpha Mus musculus 15-24 31299271-4 2019 IFN-alpha-2b-treated mice showed increased plasma cholesterol levels together with decreased hepatic cholesterol, both on chow and HF diets. Cholesterol 50-61 interferon alpha Mus musculus 0-9 31299271-4 2019 IFN-alpha-2b-treated mice showed increased plasma cholesterol levels together with decreased hepatic cholesterol, both on chow and HF diets. Cholesterol 101-112 interferon alpha Mus musculus 0-9 31299271-5 2019 Interestingly, mice on IFN-alpha-2b treatment secreted smaller VLDL particles highly enriched in cholesterol. Cholesterol 97-108 interferon alpha Mus musculus 23-32 31299271-6 2019 Mechanistically, we found that IFN-alpha-2b antiobesity effects were related to increased fatty acid oxidation; and its effects on cholesterol metabolism were due to both a decrease in the master cholesterogenic transcription factor SREBP-2 and in the rate limiting enzyme in cholesterol synthesis, HMGCR. Cholesterol 276-287 interferon alpha Mus musculus 31-40 31299271-7 2019 To our knowledge, this is the first report showing the effects of IFN-alpha-2b on the prevention of the development of HFD-induced body weight gain and dyslipidemia through a mechanism that involves fatty acid oxidation and cholesterol decrease. Cholesterol 224-235 interferon alpha Mus musculus 66-75 17307134-0 2007 Leptin restores plasma cholesterol, glucose and weight loss induced by IFNalpha treatment. Cholesterol 23-34 interferon alpha Mus musculus 71-79 17307134-7 2007 Thus, leptin co-administration with IFNalphaA/D decreases some of the side effects of IFNalpha administration such as weight loss, cholesterol and glucose levels. Cholesterol 131-142 interferon alpha Mus musculus 36-44