PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22748276-0	2012	Macrophage ABCA2 deletion modulates intracellular cholesterol deposition, affects macrophage apoptosis, and decreases early atherosclerosis in LDL receptor knockout mice.	Cholesterol	50-61	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	11-16	
22748276-1	2012	OBJECTIVE: The ABCA2 transporter shares high structural homology to ABCA1, which is crucial for the removal of excess cholesterol from macrophages and, by extension, in atherosclerosis.	Cholesterol	118-129	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	15-20	
22748276-2	2012	It has been suggested that ABCA2 sequesters cholesterol inside the lysosomes, however, little is known of the macrophage-specific role of ABCA2 in regulating lipid homeostasis in vivo and in modulating susceptibility to atherosclerosis.	Cholesterol	44-55	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	27-32	
21810484-0	2011	The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells.	Cholesterol	57-68	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	4-38	
21810484-0	2011	The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells.	Cholesterol	57-68	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	40-45	
21810484-3	2011	It is important to study the role of ABCA2 in regulating cholesterol homeostasis in neuronal-type cells because ABCA2 has been identified as a possible genetic risk factor for Alzheimer"s disease.	Cholesterol	57-68	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	37-42	
21810484-4	2011	In this study, the effects of ABCA2 expression on cholesterol homeostasis were examined in mouse N2a neuroblastoma cells.	Cholesterol	50-61	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	30-35	
21810484-5	2011	ABCA2 reduced total, free- and esterified cholesterol levels as well as membrane cholesterol but did not perturb cholesterol distribution in organelle or lipid raft compartments.	Cholesterol	42-53	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	0-5	
21810484-5	2011	ABCA2 reduced total, free- and esterified cholesterol levels as well as membrane cholesterol but did not perturb cholesterol distribution in organelle or lipid raft compartments.	Cholesterol	81-92	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	0-5	
21810484-5	2011	ABCA2 reduced total, free- and esterified cholesterol levels as well as membrane cholesterol but did not perturb cholesterol distribution in organelle or lipid raft compartments.	Cholesterol	81-92	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	0-5	
21810484-7	2011	Cholesterol trafficking to the plasma membrane was not affected by ABCA2 but efflux to the physiological acceptor ApoE3 and mobilization of plasma membrane cholesterol to the endoplasmic reticulum for esterification were reduced by ABCA2.	Cholesterol	0-11	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	232-237	
21810484-7	2011	Cholesterol trafficking to the plasma membrane was not affected by ABCA2 but efflux to the physiological acceptor ApoE3 and mobilization of plasma membrane cholesterol to the endoplasmic reticulum for esterification were reduced by ABCA2.	Cholesterol	156-167	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	232-237	
21810484-8	2011	ABCA2 reduced esterification of serum and low-density lipoprotein-derived cholesterol but not 25-hydroxycholesterol.	Cholesterol	74-85	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	0-5	
29223352-4	2018	Moreover, in macrophages ABCA2 is influenced by sterols and has a role in regulating cholesterol sequestration, potentially important in cardiovascular disease.	Cholesterol	85-96	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	25-30	
29223352-5	2018	Accumulating data indicate the critical importance of ABCA2 in mediating movement of sphingolipids within cellular compartments and these have been implicated in various aspects of cholesterol trafficking.	Cholesterol	181-192	ATP-binding cassette, sub-family A (ABC1), member 2	Mus musculus	54-59