PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17635080-6 2007 IGF-II levels were significantly higher in the SZ group (p=0.02) and correlated positively with levels of atherogenic lipoproteins--total cholesterol, low-density lipoprotein, apoB--and IGFBP-3. Cholesterol 138-149 insulin like growth factor 2 Homo sapiens 0-6 8636318-3 1996 IGF-I was not significantly associated with cardiovascular risk factors but IGF-II levels correlated positively with total and LDL cholesterol most markedly in the diet treated group (0.72, p < 0.01 and 0.76, p < 0.01 respectively). Cholesterol 131-142 insulin like growth factor 2 Homo sapiens 76-82 9549041-7 1997 Northern blot analysis further demonstrated that GH amplification of IGF-II-induced steroidogenesis can be attributed, at least partially, to enhanced IGF-II-induced cytochrome P450 cholesterol side-chain cleavage mRNA by GH. Cholesterol 182-193 insulin like growth factor 2 Homo sapiens 69-75 9549041-7 1997 Northern blot analysis further demonstrated that GH amplification of IGF-II-induced steroidogenesis can be attributed, at least partially, to enhanced IGF-II-induced cytochrome P450 cholesterol side-chain cleavage mRNA by GH. Cholesterol 182-193 insulin like growth factor 2 Homo sapiens 151-157 29724293-5 2018 Simple linear regression analysis showed that systolic blood pressure (SBP), mean arterial pressure (MAP), and levels of serum low-density lipoprotein (LDL) and cholesterol (CHOL) were related to plasma preptin levels. Cholesterol 161-172 insulin like growth factor 2 Homo sapiens 203-210 31182144-12 2019 CONCLUSION: Increased methylation level in the IGF2 gene was associated with early-life exposure to severe famine, and this change was also positively associated with total cholesterol in late adulthood. Cholesterol 173-184 insulin like growth factor 2 Homo sapiens 47-51 8396578-11 1993 IGF-II increased the abundance of ACTH-stimulated mRNAs encoding cholesterol side-chain cleavage cytochrome P450 (P450scc), 17 alpha hydroxylase/17,20 lyase P450 (P450c17), and 3 beta-hydroxysteroid dehydrogenase (3 beta HSD). Cholesterol 65-76 insulin like growth factor 2 Homo sapiens 0-6 3349907-3 1988 Fetal testicular IGF-II mRNA decreases significantly with increasing gestational age, in parallel with our previous measurements of the mRNAs for the steroidogenic enzymes P450scc (cholesterol side-chain cleavage enzyme) and P450c17 (17 alpha-hydroxylase/17,20 lyase) (J. Clin. Cholesterol 181-192 insulin like growth factor 2 Homo sapiens 17-23 3031644-8 1987 Accumulation of mRNA for the cholesterol side-chain-cleavage monooxygenase [P450scc [corrected]; cholesterol, reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving), EC 1.14.15.6] was regulated in parallel with IGF-II mRNA in all these steroidogenic tissues. Cholesterol 29-40 insulin like growth factor 2 Homo sapiens 227-233 29724293-5 2018 Simple linear regression analysis showed that systolic blood pressure (SBP), mean arterial pressure (MAP), and levels of serum low-density lipoprotein (LDL) and cholesterol (CHOL) were related to plasma preptin levels. Cholesterol 174-178 insulin like growth factor 2 Homo sapiens 203-210 27489546-0 2016 Corrigendum: Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. Cholesterol 91-102 insulin like growth factor 2 Homo sapiens 49-77 24081183-0 2014 Insulin-like growth factor-II and insulin-like growth factor binding protein-2 prospectively predict longitudinal elevation of HDL-cholesterol in type 2 diabetes. Cholesterol 131-142 insulin like growth factor 2 Homo sapiens 0-29 24081183-7 2014 HDL cholesterol at baseline was associated with log-IGF-II concentration in a model adjusted for age, gender, baseline body-mass index (BMI), estimated glomerular filtration rate (eGFR) and lipid-lowering therapy. Cholesterol 4-15 insulin like growth factor 2 Homo sapiens 52-58 24081183-9 2014 A higher circulating IGF-II concentration at baseline was also associated with longitudinal increase in HDL-cholesterol in mixed-effects regression analyses independent of IGF-I, IGFBP-1, IGFBP-2, IGFBP-3, age, gender, eGFR, BMI and lipid-lowering therapy. Cholesterol 108-119 insulin like growth factor 2 Homo sapiens 21-27 24081183-12 2014 CONCLUSION: Our analyses based on "real world" data demonstrate that higher baseline IGF-II and IGFBP-2 predict increased HDL concentration over time, implicating IGF-II in modulation of circulating HDL-cholesterol concentrations. Cholesterol 203-214 insulin like growth factor 2 Homo sapiens 163-169