PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26901218-8 2016 Thus, genes controlling the turnover of vitamin D (CYP27B1, CYP24A1), vitamin A (ALDH1A3, AKR1B10), and cholesterol (CYP7B1), were up-regulated in psoriasis, whereas melanomas showed downregulation of genes regulating turnover of vitamin A (AKR1C3), and cholesterol (CYP39A1). Cholesterol 104-115 cytochrome P450 family 39 subfamily A member 1 Homo sapiens 267-274 20699090-14 2010 Synthesis of BAs from cholesterol occurs either via the classical pathway (7alpha-hydroxylation of cholesterol; CYP7A1) or via the alternate pathway (CYP39A1 or CYP7B1). Cholesterol 22-33 cytochrome P450 family 39 subfamily A member 1 Homo sapiens 150-157 12398993-2 2002 In liver, 7 alpha-hydroxylation of cholesterols, mediated by CYP7A and CYP39A1, is the rate-limiting step of bile acid synthesis and metabolic elimination. Cholesterol 35-47 cytochrome P450 family 39 subfamily A member 1 Homo sapiens 71-78 32392803-3 2020 Conversion of cholesterol to 24S-OHC is mediated by cholesterol 24S-hydroxylase in the brain, which is the major pathway for oxysterol elimination, followed by oxidation through hepatic first-pass metabolism by CYP39A1. Cholesterol 14-25 cytochrome P450 family 39 subfamily A member 1 Homo sapiens 211-218