PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21343306-4 2011 Here, we identify two ER membrane proteins, SPFH2 and TMUB1, as associated proteins of mammalian gp78, a membrane-bound ubiquitin ligase that bears significant sequence homology with mammalian Hrd1 and mediates sterol-accelerated ERAD of the cholesterol biosynthetic enzyme HMG-CoA reductase. Cholesterol 242-253 ER lipid raft associated 2 Homo sapiens 44-49 16835267-3 2006 Two of these proteins, KE04p and C8orf2, were found to be highly enriched in the detergent-insoluble, buoyant fraction of sucrose gradients in a cholesterol-dependent manner. Cholesterol 145-156 ER lipid raft associated 2 Homo sapiens 33-39