PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32229726-0	2020	Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.	Cholesterol	79-90	Rho associated coiled-coil containing protein kinase 2	Homo sapiens	24-29	
32229726-7	2020	ATAC-Seq (assay for transposase-accessible chromatin with high-throughput sequencing) and biochemical analyses revealed that the effects of ROCK2 on cholesterol biosynthesis were instead mediated via a novel mechanism.	Cholesterol	149-160	Rho associated coiled-coil containing protein kinase 2	Homo sapiens	140-145	
32229726-8	2020	ROCK2 directly phosphorylated interferon regulatory factor 8 (IRF8), a crucial mediator of GC responses, and promoted its interaction with sterol regulatory element-binding transcription factor 2 (SREBP2) at key regulatory regions controlling the expression of cholesterol biosynthetic enzymes, resulting in optimal recruitment of SREBP2 at these sites.	Cholesterol	261-272	Rho associated coiled-coil containing protein kinase 2	Homo sapiens	0-5	
32229726-5	2020	RNA-Seq analyses revealed that ROCK2 controlled a unique transcriptional program in GC B cells that promoted optimal GC polarization and cholesterol biosynthesis.	Cholesterol	137-148	Rho associated coiled-coil containing protein kinase 2	Homo sapiens	31-36